RAD-140 (Testolone) SARM – Cycle, Dosage, Results and Side Effects

The most powerful. One of the most studied. Possibly, the most popular. RAD-140, aka Testolone, defines what SARMs are all about. Here is how to get the best of it - and what you should brace for on the side effects part.


RAD-140 is a classic bulking SARM. It’s often referred to as the non-steroidal Testosterone in a pill, and the market name Testolone just adds to the confusion. While it’s probably a rare example of single-purpose bulking SARM, it still has a ton of difference from the King of steroids – both positive and negative. Here they are – and how to get the best of RAD-140. 

What Is RAD 140

The compound belongs to the class of Selective Androgenic Receptor Modulators. These are non-steroidal performance boosters that attach to a LIMITED number of your androgenic receptors in a specific body area (muscles) and stimulate muscle growth. While anabolic steroids cause all kinds of effects in all parts of your body, SARMs act selectively and don’t mess up your hormonal levels at all. 

SARMs are generally weaker than AAS, but it’s not the case with RAD-140. Testolone was developed precisely to replace Testosterone in the future of TRT (Testosterone Replacement Therapy) itself.

Testolone vs. Testosterone 

First of all, comparing these two substances FOR REAL is just as ridiculous as comparing Donald Trump to Donald Duck. The names sound the same, but these are two completely different guys. RAD-140 Testolone and Testosterone can genuinely compete in just one aspect: anabolic activity, aka muscle building potential. 

As you know, Testosterone is the golden standard of modern performance enhancement compounds. It’s 100% anabolic and 100% androgenic – with a 100:100 ratio. 

RAD-140 has an outstanding (for a SARM) anabolic-androgenic ratio of about 90:1. You can roughly translate the numbers to «Almost as strong in muscle growth boost as Testosterone but zero to none androgenic side effects». Even though these numbers are approximate, it’s still a great power.

That’s why the marketing guys deserve a round of applause – they clearly knew what they were doing. Testolone is a unique case when the wordplay is justified.

RAD-140 Benefits  

Now – to the best part of it. This is what RAD-140 can give you in a single cycle: 

Muscle Growth 

RAD-140 has no second trait, no other purpose, but pure bulking. You either use it for mass growth, or you cycle something else, because making you big is where Testolone shines best. 

In early trials, it has shown that even 10mg per day, for four weeks, would be enough to give 10% extra body weight to a 100kg (220 lbs) man. 

Again: Just a mere 0,1mg per kilo can give you over 10 kilos (22 lbs) of mass in a month. 

Of course, it’s all individual, it’s not a dry muscle mass, and we’re talking about monkey trials. However, it’s still an outstandingly rapid growth in a relatively short term. 

Bones Health Improvement 

You can make your skeleton pretty happy on RAD-140 – and it’s been medically proven by studies, like this one. Even though the compound was never made for people with bone structure issues (like osteoporosis), you can get some practical benefits from it: 

  • Bone density improvement; 
  • Faster bone tissue growth; 
  • Faster bone-related traumas healing. 

Health Protection 

No SARMs were developed with your biceps size in mind. RAD-140 was invented as a revolution of testosterone replacement therapy. No, blasting 750mg of Testosterone Enanthate is not a TRT. It’s madness. TRT is a medical thing, more of a treatment for multiple hormonal diseases and disorders, that men tend to get with age. That’s why, in addition to making you massive, RAD-140 will also: 

  • Protect your breast tissue from cancer development, which is always a nice thing, especially if you cycle aromatizable AAS as well. Here you can read the full study on the issue; 
  • Protect your brain from getting weaker with age (and you from getting dumber, clinically) by combating neurodegenerative diseases. At least, it worked like that with rats in this study
  • Protect your prostate from getting larger, which can lead to another kind of cancer and tragic chain reactions all around your body. In these trials, RAD-140 was proven to be a soothing balm for your prostate. 

Others RAD-140 Benefits

These were all the effects we can prove clinically. However, the anecdotal experience of hundreds of athletes worldwide says that there’s more to the compound. In addition to all the nice things above and crazy bulking, you may – or may not (we can’t trust the reports for 100%) also get: 

  • Increased pumping during the workouts and by literally holding the steering wheel on your rest days; 
  • Harder muscle, especially dense and notable in lean athletes with low body fat; 
  • Incredible strength gains that will send your weights through the roof. 

Sounds good, but hardly works with everyone. Anyway, extreme bulking is STILL the primary benefit of RAD-140 and the one you should pay the most attention to. Now – to the practical part of it. 

RAD-140 Dosage 

In early-stage trials, patients (post-menopausal women, not athletes) were given up to 150mg of RAD-140. The target was to set dosage frames and find the exact spot where side effects would take over the benefits. 

The point of no return is 100mg per day. 

That’s the top for a human being. Some gym monsters cycle up to 150mg, but it’s a questionable thing. In doses over 100mg, you start losing the anabolic effect, while risks of severe cardiovascular side effects start to grow. At least, that’s what medical data tells us. 

In bodybuilding (where you rarely see post-menopausal women), the most popular doses are between 20 and 100mg. In these frames, you don’t get extreme BP spikes with blurred vision in the process. Given the extreme anabolic potential, I would even say that the absolute majority of athletes rarely go over 30mg ED. 

Find your sweet spot between 20 and 100mg every day through experiments from low to high, and don’t listen to anyone. Nobody knows what’s best for YOU, except yourself. 

How To Take RAD-140 

The compound is oral. It comes in pills. You know what to do with pills. 

RAD-140 oral form’s best thing is that you don’t need injections, and STILL get excellent bioavailability. Practically, all the active substance reaches the target, as we know from the preclinical characterization

When To Take RAD-140 

The substance has a half-life of about 60 hours, and in some cases – it can be extended to over 5 days. It does NOT mean that you need a unique protocol for Testolone. The everyday scheme is still the best. This way, you smooth all the positive and harmful effects. 

RAD-140 PCT 

Yes, even though it’s not steroidal, you need serious post-cycle therapy after RAD-140.

Nolvadex or Clomid in medium dosage, up to 40mg per day, is a primary choice for most, since the regular 20mg ED won’t work for everyone. 

It would help if you had longer PCT as well – aim at 4 weeks, and lower the dose to 20mg in the last two. This s not necessary, and the regular 2 weeks 20mg Nolva can work for you just as good. It all depends on the personal response. Just keep in mind that you need a bit more, and adjust the PCT for your comfort. 

The good thing is, you don’t need to wait for a day to start the PCT. Just hop on Nolva right on the next day of your last RAD-140 pill. 

A couple of weeks break between is also important. Don’t be a dick to your body and give it a little rest. 

Best RAD-140 Cycles 

RAD-140 is a pure bulker, so I’ll give you a bulking cycle first. 

RAD-140 Bulking Cycle 

This is what the protocol would look like. You can take it as it is, or adjust it to your personal preferences: 

WeeksRAD-140 TestoloneNolvadex PCT
Week 1-620-50mg ED
Weeks 7-840mg ED
Weeks 9-1020mg ED

Quite obviously, you can run a 100mg ED dose if the numbers in the table don’t work for you. You can shorten – or prolong – the cycle itself by a couple of weeks, and lower the Nolva dose as well. 

RAD-140 Cutting Cycle 

There is no such thing. If you want cutting and fat-melting effects, switch to Cardarine. Utilizing such a potent mass growth compound for cutting and framing it with a calorie deficit is like paying a hooker for hugs, going to rehab for parties, or riding a bike with your hands on the pedals. It will probably work, but you look retarded in the process, and the result could be way better if you used things right.

Best RAD-140 Stacks 

Given that it’s a bulker, the best compounds for a stack are potent on the anabolic side as well: 

Powerful Bulking RAD-140 and MK-677 Stack 

You can run two compounds at a time and get excellent results. For example, this is a RAD-140 and MK-677 stack with MK-677 Ibutamoren:

WeeksRAD-140 TestoloneMK-677 IbutamorenNolvadex PCT
Week 1-820-30mg ED20mg ED
Weeks 9-1040mg ED
Weeks 11-1220mg ED

MK-677 is a growth hormone promotant, closer by its mechanism of action to peptides, instead of SARMs. You don’t need a PCT after MK-677. However, you NEED it after RAD140, so, for the sake of the size of your own balls, don’t skip the thing. 

Extreme Mass Growth RAD-140 Stack With LGD-4033 and MK-677 

As humans, we are curious by nature. So, the question «What if I stack 3 of the most compounds of the class together» was just a matter of time. The answer is – extreme visual blow up and body transformation in one cycle. Here is how the said stack would look like: 

WeekMK-677Rad-140 TestoloneLGD-4033 LigandrolNolvadex PCT 
Weeks 1-625mg ED20mgED10-20mg ED
Weeks 7-840mg ED
Weeks 9-1020-40mg ED

In a stack like that, keep doses of each compound low. Possibly – even lower than they are given in the table, and be sure to KNOW how your body reacts to each of them separately. 

You need some experience under your belt to avoid situations when you have to drop the whole cycle, unable to identify, which of the compounds gives you nightmares and 16-hours-long erections. Spoiler alert: it’s most likely not RAD-140.

RAD-140 Side Effects 

Oh boy, there are plenty, but not all of them are obvious. Let’s take a closer look, one by one. 

Ventricular Inflammation 

In medical terms, inflammation means that metabolism in some parts of your body has gone wrong, and now the tissue is destroying itself. It gets red, gets swollen, and basically dies. 

Sounds scary, and you don’t want your heart to be even in the same sentence with this? Well, unfortunately, this study puts the two together. 

While it’s probably the most quoted study on RAD-140 on all bodybuilding forums, it has some issues: 

  1. It’s a rat study, which should always be taken with a grain of salt; 
  2. The same thing on monkeys didn’t work, no ventricular inflammation even on extremely high doses; 
  3. In early-stage human trials (the one with post-menopausal women), it occurred rarely, and only on 150mg per day dose, in the 8 weeks cycle. 

What can you do about it? Stay in healthy frames and don’t exceed the 100mg daily dose. Maybe, don’t exceed over the 50mg as well, if it works for you. Extra attention to your heart during the cycle would be nice as well. 

Vision Issues

One of the most notable side effect, because, like… you literally can’t unsee it. The effect is likely linked to intraocular pressure changes, but we have insufficient medical data on the subject. According to anecdotal reports, Testolone can cause: 

  • Harder concentration;
  • «Blind spots»;  
  • Blurred vision; 
  • Shaky picture in front of your eyes;
  • White «flies»; 
  • Impaired vision in poor lighting. 

Luckily, all of it disappears when you finish the cycle, and rarely manifests in the first hand. The only thing you can do is lower your dose significantly. If it doesn’t work or makes the cycle useless, just drop the whole thing and switch to a different SARM – we have no 100% working means of combating this side effect. 

Just don’t switch to S4, aka Andarine – it’s the most «vision fuckery»-famous SARM. It will add a bright yellow tint to every blurry and shaky detail of the world in front of your eyes.  


RAD-140 is not precisely «fury in a pill», but for some athletes – somehow – it’s an aggression trigger. Many even say that it’s the most «aggressive» SARM of all. Unfortunately, something tells me that we’ll surely never get a full-scale study on that. 

Other Side Effects

Here are other notable side effects that were mentioned in multiple anecdotal reports, but weren’t proven clinically: 

  • Headaches; 
  • BP spikes; 
  • Dizziness; 
  • Reduced stamina; 
  • Water retention.

You will not necessarily get any of them, but you’ve got to be prepared anyway. RAD-140 is still under massive control and in the center of many studies. For example, this one from January 2020 suggests that it’s liver toxic. If you decide to cycle Testolone, make sure to at least Google it first – new crucial studies can appear at any moment, and the situation will remain uncertain for years. 

Personal Opinion On RAD-140 Testolone

The only personal opinion you are officially allowed to have on RAD-140 is «Don’t even think about cycling RAD-140! It’s NOT approved for humans! It’s STILL in trials! It’s dangerous!». Yes, that’s the only opinion that Health Canada (and FDA) would appreciate. While all the statements are not far from true, this approach is too far from reality. The substance is already on the market, it’s already popular as hell, and there’s pretty much nothing you can do about it. 

As for me, RAD-140 is worth giving it a try, but your head should stay cold all the time, and the control of your health and the situation, in general, should be on top alert. Like, not a single little tingling should be left without attention. You can relax a bit only after you jump off the cycle, run a proper PCT, and keep clean for a few weeks. In my opinion, that’s the only way one should act to get all the outstanding benefits of RAD-140 and stay safe. 


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